Known components of the cellulosome of Clostridium thermocellum (a)

Cellulosome Components (b)	Description	Modular Structure	Molecular Mass (kDa)
CipA (c)	Scaffoldin	2(Coh1)-CBM3a-7(Coh1)-X2-DocII	197
CelJ	Cellulase	X-Ig-GH9-GH44-DocI-X	178
CbhA	Cellobiohydrolase	CBM4-Ig-GH9-2(Fn3)-CBM3b-DocI	138
XynY	Xylanase	CBM22-GH10-CBM22-DocI-CE1	120
CelH	Endoglucanase	GH26-GH5-CBM9-DocI	102
CelK	Cellobiohydrolase	CBM4-Ig-GH9-DocI	101
XynZ	Xylanase	CE1-CBM6-DocI-GH10	92
CelE	Endoglucanase	GH5 - DocI - CE2	90
CelS (c)	Exoglucanase	GH48 - DocI	83
CelF	Endoglucanase	GH9-CBM3c-DocI	82
CelN	Endoglucanase	GH9-CBM3c-DocI	82
CelQ	Endoglucanase	GH9-CBM3c-DocI	82
CelO	Cellobiohydrolase	CBM3a-GH5- DocI	75
XynA, XynU	Xylanase	GH11-CBM4-DocI-NodB	74
CelD	Endoglucanase	Ig - GH9 - DocI	72
XynC	Xylanase	CBM22-GH10-DocI	70
XynD	Xylanase	CBM22-GH10-Doc1	70
ManA	Mannanase	CBM-GH26-DocI	67
CelT	Endoglucanase	GH9 - DocI	65
CelB	Endoglucanase	GH5 - DocI	64
CelG	Endoglucanase	GH5 - DocI	63
CseP	Unknown	UN - DocI	62
ChiA	Chitinase	GH18 - DocI	55
CelA	Endoglucanase	GH8 - DocI	53
XynB, XynV	Xylanase	GH11-CBM4-DocI	50
LicB	Lichenase	GH16 - DocI	38

Components are sorted according to their molecular mass. (a) Modified and updated from(1). (b) Components in bold letters: Localisation in the cellulosom was experimentally shown. (c) Main components

Abbreviations : CE, carbohydrate esterase; CBM, substrate binding module; Coh1, typ-I cohesin module; DocI, typ-I dockerin module; FAE, ferulic acid esterase; GH, glycosyl hydrolase (family); Ig, immunoglobulin-like module; UN, unknown module; X, hydrophobic module with unknown function.

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