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Prof. Dr. Bernhard Küster

Position: Head Küster
Room: 105
Category: Scientific Staff
Phone: +49 - (0)8161 - 715696
Email:

Curriculum Vitae

Curriculum_Vitae_Kuster.pdf


Publications

Quantitative Proteome Profiling of human Myoma and Myometrium tissue reveals kinase expression signatures with potential for therapeutic intervention.

Proteomics. 2014 Oct 18. doi: 10.1002/pmic.201400213. [Epub ahead of print] DOI: -
Lemeer S | 1 | Gholami AM | Wu Z | Kuster B
Online reference

Tracking cancer drugs in living cells by thermal profiling of the proteome

Science 2014 Oct 3;346(6205):1255784. DOI: 10.1126/science.1255784
Savitski MM | Reinhard FB | Franken H | Werner T | Savitski MF | Eberhard D | Martinez Molina D | Jafari R | Dovega RB | Klaeger S | Kuster B | Nordlund P | Bantscheff M | Drewes G
Online reference

Ion mobility tandem mass spectrometry enhances performance of bottom-up proteomics.

Mol Cell Proteomics. 2014 Aug 8. pii: mcp.M114.041038. [Epub ahead of print] 2014 Aug 8 DOI: -
Helm D | Vissers JP | Hughes CJ | Hahne H | Ruprecht B | Pachl F | Grzyb A | Richardson K | Wildgoose J | Maier SK | Marx H | Wilhelm M | Becher I | Lemeer S | Bantscheff M | Langridge JI | Kuster B
Online reference

A multivariate approach to the integration of multi-omics datasets.

BMC Bioinformatics. 2014 May 29;15(1):162 DOI: 10.1186/1471-2105-15-162
Meng C | Kuster B | Culhane AC | Moghaddas Gholami A
Online reference

Plant cytokinesis is orchestrated by the sequential action of the TRAPPII and exocyst tethering complexes

Dev Cell 2014 Jun 9;29(5):607-20 DOI: 10.1016/j.devcel.2014.04.029
Rybak K | Steiner A | Synek L | Klaeger S | Kulich I | Facher E | Wanner G | Kuster B | Zarsky V | Persson S | Assaad FF
Online reference

Mass-spectrometry-based draft of the human proteome

Nature 2014 May 29;509(7502):582-7. DOI: 10.1038/nature13319.
Wilhelm M | Schlegl J | Hahne H | Moghaddas Gholami A | Lieberenz M | Savitski MM | Ziegler E | Butzmann L | Gessulat S | Marx H | Mathieson T | Lemeer S | Schnatbaum K | Reimer U | Wenschuh H | Mollenhauer M | Slotta-Huspenina J | Boese JH | Bantscheff M | Gerstmair A | Faerber F | Kuster B
Online reference

PAS-cal: a Generic Recombinant Peptide Calibration Standard for Mass Spectrometry.

J Am Soc Mass Spectrom. 2014 Aug;25(8):1489-97 DOI: 1007/s13361-014-0902-3
Breibeck J | Serafin A | Reichert A | Maier S | Kuester B | Skerra A | Munich Center for Integrated Protein Science, CIPS-M, and Lehrstuhl für Biologische Chemie, Technische Universität München, 85350, Freising-Weihenstephan, Germany.
Online reference

New Affinity Probe Targeting VEGF Receptors for Kinase Inhibitor Selectivity Profiling by Chemical Proteomics.

J Proteome Res. 2014 May 2;13(5):2445-52 DOI: 10.1021/pr40124t
Ku X | Heinzlmeir S | Helm D | Médard G | Kuster B
Online reference

A new chemical probe for quantitative proteomic profiling of fibroblast growth factor receptor and its inhibitors.

J Proteomics 2014 Jan;96:44-55. DOI: 10.1016/j.jprot.2013.10.031
Ku X | Heinzlmeir S | Liu X | Médard G | Kuster B
Online reference

High-fat diet alters gut microbiota physiology in mice.

ISME J. 2014 Feb;8(2):295-308 DOI: 10.1038/ismej.2013.155
Daniel H | Gholami AM | Berry D | Desmarchelier C | Hahne H | Loh G | Mondot S | Lepage P | Rothballer M | Walker A | Böhm C | Wenning M | Wagner M | Blaut M | Schmitt-Kopplin P | Kuster B | Haller D | Clavel T
Online reference

DMSO enhances electrospray response, boosting sensitivity of proteomic experiments.

Nat Methods. 2013 Oct 10(10):989-91 DOI: 10.1038/nmeth.2610
Hahne H | Pachl F | Ruprecht B | Maier SK | Klaeger S | Helm D | Médard G | Wilm M | Lemeer S | Kuster B
Online reference

Global Proteome Analysis of the NCI-60 Cell Line Panel.

Cell Rep. 2013 Aug 15;4(3):609-20. Epub 2013 Aug 8. DOI: 10.1016/j.celrep.2013.07.018
Gholami AM | Hahne H | Wu Z | Auer FJ | Meng C | Wilhelm M | Kuster B
Online reference

Characterization of a high field Orbitrap mass spectrometer for proteome analysis.

Proteomics. 2013 Jul 8. doi: 10.1002/pmic.201300076. [Epub ahead of print] DOI: -
Pachl F | Ruprecht B | Lemeer S | Kuster B
Online reference

Characterization of a Chemical Affinity Probe Targeting Akt Kinases.

J Proteome Res. 2013 Aug 2;12(8):3792-800 DOI: 10.1021/pr400455j
Pachl F | Plattner P | Ruprecht B | Médard G | Sewald N | Kuster B
Online reference

Comprehensive identification of proteins from MALDI imaging.

Mol Cell Proteomics. 2013 Jun 19. [Epub ahead of print] DOI: -
Maier SK | Hahne H | Moghaddas Gholami A | Balluff B | Meding S | Schoene C | Walch AK | Kuster B | Source | Technische Universitaet Muenchen, Germany;
Online reference

Co-immunoprecipitation-based identification of putative BAX INHIBITOR-1-interacting proteins involved in cell death regulation and plant-powdery mildew interactions.

Mol Plant Pathol. 2013 Jun 19. doi: 10.1111/mpp.12050. [Epub ahead of print] DOI: -
Weis C | Pfeilmeier S | Glawischnig E | Isono E | Pachl F | Hahne H | Kuster B | Eichmann R | Hückelhoven R
Online reference

Measuring and Managing Ratio Compression for Accurate iTRAQ/TMT Quantification.

J Proteome Res. 2013 Jul 2. [Epub ahead of print] DOI: -
Savitski MM | Mathieson T | Zinn N | Sweetman G | Doce C | Becher I | Pachl F | Kuster B | Bantscheff M
Online reference

A large synthetic peptide and phosphopeptide reference library for mass spectrometry-based proteomics.

Nat Biotechnol. 2013 May 19. doi: 10.1038/nbt.2585. [Epub ahead of print] DOI: -
Marx H | Lemeer S | Schliep JE | Matheron L | Mohammed S | Cox J | Mann M | Heck AJ | Kuster B
Online reference

MScDB: A Mass Spectrometry Centric Protein Sequence Database for Proteomics.

J Proteome Res. 2013 Apr 30. [Epub ahead of print] DOI: -
Marx H | Lemeer S | Klaeger S | Rattei T | Kuster B
Online reference

Clinical response to chemotherapy in oesophageal adenocarcinoma patients is linked to defects in mitochondria.

J Pathol. 2013 Apr 16. doi: 10.1002/path.4199. [Epub ahead of print] DOI: -
Aichler M | Elsner M | Ludyga N | Feuchtinger A | Zangen V | Maier SK | Balluff B | Schöne C | Hierber L | Braselmann H | Meding S | Rauser S | Zischka H | Aubele M | Schmitt M | Feith M | Hauck SM | Ueffing M | Langer R | Kuester B | Zitzelsberger H | Höfler H | Walch AK | Source | Research Unit Analytical Pathology - Institute of Pathology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.
Online reference

Comparing immobilized kinase inhibitors and covalent ATP probes for proteomic profiling of kinase expression and drug selectivity.

J Proteome Res. 2013 Mar 15. [Epub ahead of print] DOI: -
Lemeer S | Ruprecht B | Zörgiebel C | Kohl K | Kuster B
Online reference

Proteome wide purification and identification of O-GlcNAc modified proteins using Click chemistry and mass spectrometry.

J Proteome Res. 2013 Jan 9. [Epub ahead of print] DOI: -
Hahne H | Sobotzki N | Nyberg T | Helm D | Borodkin VS | van Aalten DM | Agnew B | Kuster B
Online reference

A public-private partnership to unlock the untargeted kinome

Nat Chem Biol. 2013 Jan;9(1):3-6. DOI: 10.1038/nchembio.1113
Knapp S | Arruda P | Blagg J | Burley S | Drewry DH | Edwards A | Fabbro D | Gillespie P | Gray NS | Kuster B | Lackey KE | Mazzafera P | Tomkinson NC | Willson TM | Workman P | Zuercher WJ.
Online reference

SCF(Fbxo9) and CK2 direct the cellular response to growth factor withdrawal via Tel2/Tti1 degradation and promote survival in multiple myeloma.

Nat Cell Biol. 2012 Dec 23. doi: 10.1038/ncb2651. [Epub ahead of print] DOI: -
Fernández-Sáiz V | Targosz BS | Lemeer S | Eichner R | Langer C | Bullinger L | Reiter C | Slotta-Huspenina J | Schroeder S | Knorn AM | Kurutz J | Peschel C | Pagano M | Kuster B | Bassermann F
Online reference

A Simple and Effective Cleavable Linker for Chemical Proteomics Applications.

Mol Cell Proteomics. 2012 Oct 1. [Epub ahead of print] DOI: -
Yang Y | Hahne H | Kuster B | Verhelst SH
Online reference

Discovery of O-GlcNAc-6-phosphate-modified proteins by re-analyzing large-scale phosphoproteomics data.

Mol Cell Proteomics. 2012 Jul 23. [Epub ahead of print] DOI: -
Hahne H | Kuster B
Online reference

Quantitative mass spectrometry in proteomics.

Anal Bioanal Chem. 2012 Sep;404(4):937-8. DOI: 10.1007/s00216-012-6261-7
Bantscheff M | Kuster B.
Online reference

Quantitative mass spectrometry in proteomics: critical review update from 2007 to the present.

Anal Bioanal Chem. 2012 Sep;404(4):939-65. doi: 10.1007/s00216-012-6203-4. Epub 2012 Jul 8. DOI: -
Bantscheff M | Lemeer S | Savitski MM | Kuster B
Online reference

MALDI Imaging Mass Spectrometry for In Situ Proteomic Analysis of Preneoplastic Lesions in Pancreatic Cancer.

PLoS One. 2012;7(6):e39424. Epub 2012 Jun 26. DOI: -
Grüner BM | Hahne H | Mazur PK | Trajkovic-Arsic M | Maier S | Esposito I | Kalideris E | Michalski CW | Kleeff J | Rauser S | Schmid RM | Küster B | Walch A | Siveke JT
Online reference

Discovery of O-GlcNAc-modified proteins in published large-scale proteome data.

Mol Cell Proteomics. 2012 Jun 1. [Epub ahead of print] DOI: -
Hahne H | Gholami AM | Kuster B
Online reference

Ultra-high intra-spectrum mass accuracy enables unambiguous identification of fragment reporter ions in isobaric multiplexed quantitative proteomics.

Proteomics. 2012 May;12(9):1328-32. doi: 10.1002/pmic.201100622. DOI: -
Pachl F | Fellenberg K | Wagner C | Kuster B
Online reference

Lactocepin secreted by lactobacillus exerts anti-inflammatory effects by selectively degrading proinflammatory chemokines.

Cell Host Microbe. 2012 Apr 19;11(4):387-96. DOI: -
von Schillde MA | Hörmannsperger G | Weiher M | Alpert CA | Hahne H | Bäuerl C | van Huynegem K | Steidler L | Hrncir T | Pérez-Martínez G | Kuster B | Haller D
Online reference

Carbonyl-reactive tandem mass tags for the proteome-wide quantification of N-linked glycans.

Anal Chem. 2012 Mar 28. [Epub ahead of print] DOI: -
Hahne H | Neubert P | Kuhn K | Etienne C | Bomgarden RD | Rogers JC | Kuster B
Online reference

MALDI imaging mass spectrometry reveals COX7A2, TAGLN2 and S100-A10 as novel prognostic markers in Barrett\'s adenocarcinoma.

J Proteomics. 2012 Aug 3;75(15):4693-704. doi: 10.1016/j.jprot.2012.02.012. Epub 2012 Feb 17. DOI: -
Elsner M | Rauser S | Maier S | Schöne C | Balluff B | Meding S | Jung G | Nipp M | Sarioglu H | Maccarrone G | Aichler M | Feuchtinger A | Langer R | Jütting U | Feith M | Küster B | Ueffing M | Zitzelsberger H | Höfler H | Walch A
Online reference

Systematic identification of the HSP90 regulated proteome.

Mol Cell Proteomics. 2012 Feb 14. [Epub ahead of print] DOI: -
Wu Z | Moghaddas Gholami A | Kuster B
Online reference

Phosphotyrosine mediated protein interactions of the discoidin domain receptor 1.

J Proteomics. 2011 Oct 26. [Epub ahead of print] DOI: -
Lemeer S | Bluwstein A | Wu Z | Leberfinger J | Müller K | Kramer K | Kuster B
Online reference

Phosphorylation site localization in peptides by MALDI MS/MS and the Mascot Delta Score.

Anal Bioanal Chem. 2012 Jan;402(1):249-60. Epub 2011 Oct 25. DOI: -
Lemeer S | Kunold E | Klaeger S | Raabe M | Towers MW | Claudes E | Arrey TN | Strupat K | Urlaub H | Kuster B
Online reference

Quantitative chemical proteomics reveals new potential drug targets in head and neck cancer.

Mol Cell Proteomics. 2011 Sep 28. [Epub ahead of print] DOI: -
Wu Z | Doondeea JB | Moghaddas Gholami A | Janning MC | Lemeer S | Kramer K | Eccles SA | Gollin SM | Grenman R | Walch A | Feller SM | Kuster B
Online reference

Enterococcus faecalis Metalloprotease Compromises Epithelial Barrier and Contributes to Intestinal Inflammation.

Gastroenterology. 2011 May 26. [Epub ahead of print] DOI: -
Steck N | Hoffmann M | Sava IG | Kim SC | Hahne H | Tonkonogy SL | Mair K | Krueger D | Pruteanu M | Shanahan F | Vogelmann R | Schemann M | Kuster B | Sartor RB | Haller D
Online reference

A Novel Two-Stage Tandem Mass Spectrometry Approach and Scoring Scheme for the Identification of O-GlcNAc Modified Peptides.

J Am Soc Mass Spectrom. 2011 May;22(5):931-42. Epub 2011 Mar 26. DOI: -
Hahne H | Kuster B
Online reference

Confident phosphorylation site localization using the Mascot Delta Score.

Mol Cell Proteomics. 2010 Nov 6. [Epub ahead of print] DOI: -
Savitski MM | Lemeer S | Boesche M | Lang M | Mathieson T | Bantscheff M | Kuster B
Online reference

Confident phosphorylation site localization using the Mascot Delta Score.

Mol Cell Proteomics. 2011 Feb;10(2):M110.003830. Epub 2010 Nov 6. DOI: -
Savitski MM | Lemeer S | Boesche M | Lang M | Mathieson T | Bantscheff M | Kuster B
Online reference

Proteomics: a pragmatic perspective.

Nat Biotechnol. 2010 Jul;28(7):695-709. Epub 2010 Jul 9. DOI: -
Mallick P | Kuster B
Online reference

Software Tools for MS-Based Quantitative Proteomics: A Brief Overview.

Methods Mol Biol. 2012;893:489-99. DOI: -
Lemeer S | Hahne H | Pachl F | Kuster B
Online reference

Affinity purification of proteins binding to kinase inhibitors immobilized on self-assembling monolayers.

Methods Mol Biol. 2012;795:149-60. DOI: -
Bantscheff M | Hobson S | Kuster B
Online reference

Bacterial production and functional characterization of the Fab fragment of the murine IgG1/{lambda} monoclonal antibody cmHsp70.1, a reagent for tumour diagnostics.

Protein Eng Des Sel. 2010 Feb 1. DOI: 10.1093/protein/gzp095
Friedrich L | Stangl S | Hahne H | Kuster B | Köhler P | Multhoff G | Skerra A
Online reference

Oxidative stress modulates theophylline effects on steroid responsiveness.

Biochem. Biophys. Res. Commun. 2008 Dec 19; 377(3):797-802. Epub 2008 Oct 23. DOI: 10.1016/j.bbrc.2008.10.065
Marwick JA | Wallis G | Meja K | Kuster B | Bouwmeester T | Chakravarty P | Fletcher D | Whittaker PA | Barnes PJ | Ito K | Adcock IM | Kirkham PA
Online reference

Robust and sensitive iTRAQ quantification on an LTQ Orbitrap mass spectrometer.

Mol Cell Proteomics. 2008 Sep; 7(9):1702-13. Epub 2008 May 29. DOI: 10.1074/mcp.M800029-MCP200
Bantscheff M | Boesche M | Eberhard D | Matthieson T | Sweetman G | Kuster B
Online reference

Human Proteinpedia enables sharing of human protein data.

Nat Biotechnol. 2008 Feb; 26(2):164-7. DOI: 10.1038/nbt0208-164
Mathivanan S | Ahmed M | Ahn NG | Alexandre H | Amanchy R | Andrews PC | Bader JS | Balgley BM | Bantscheff M | Bennett KL | Björling E | Blagoev B | Bose R | Brahmachari SK | Burlingame AS | Bustelo XR | Cagney G | Cantin GT | Cardasis HL | Celis JE | Chaerkady R | Chu F | Cole PA | Costello CE | Cotter RJ | Crockett D | DeLany JP | De Marzo AM | DeSouza LV | Deutsch EW | Dransfield E | Drewes G | Droit A | Dunn MJ | Elenitoba-Johnson K | Ewing RM | Van Eyk J | Faca V | Falkner J | Fang X | Fenselau C | Figeys D | Gagné P | Gelfi C | Gevaert K | Gimble JM | Gnad F | Goel R | Gromov P | Hanash SM | Hancock WS | Harsha HC | Hart G | Hays F | He F | Hebbar P | Helsens K | Hermeking H | Hide W | Hjernø K | Hochstrasser DF | Hofmann O | Horn DM | Hruban RH | Ibarrola N | James P | Jensen ON | Jensen PH | Jung P | Kandasamy K | Kheterpal I | Kikuno RF | Korf U | Körner R | Kuster B | Kwon MS | Lee HJ | Lee YJ | Lefevre M | Lehvaslaiho M | Lescuyer P | Levander F | Lim MS | Löbke C | Loo JA | Mann M | Martens L | Martinez-Heredia J | McComb M | McRedmond J | Mehrle A | Menon R | Miller CA | Mischak H | Mohan SS | Mohmood R | Molina H | Moran MF | Morgan JD | Moritz R | Morzel M | Muddiman DC | Nalli A | Navarro JD | Neubert TA | Ohara O | Oliva R | Omenn GS | Oyama M | Paik YK | Pennington K | Pepperkok R | Periaswamy B | Petricoin EF | Poirier GG | Prasad TS | Purvine SO | Rahiman BA | Ramachandran P | Ramachandra YL | Rice RH | Rick J | Ronnholm RH | Salonen J | Sanchez JC | Sayd T | Seshi B | Shankari K | Sheng SJ | Shetty V | Shivakumar K | Simpson RJ | Sirdeshmukh R | Siu KW | Smith JC | Smith RD | States DJ | Sugano S | Sullivan M | Superti-Furga G | Takatalo M | Thongboonkerd V | Trinidad JC | Uhlen M | Vandekerckhove J | Vasilescu J | Veenstra TD | Vidal-Taboada JM | Vihinen M | Wait R | Wang X | Wiemann S | Wu B | Xu T | Yates JR | Zhong J | Zhou M | Zhu Y | Zurbig P | Pandey A
Online reference

Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors.

Nat Biotechnol. 2007 Sep; 25(9):1035-44. Epub 2007 Aug 26. DOI: 10.1038/nbt1328
Bantscheff M | Eberhard D | Abraham Y | Bastuck S | Boesche M | Hobson S | Mathieson T | Perrin J | Raida M | Rau C | Reader V | Sweetman G | Bauer A | Bouwmeester T | Hopf C | Kruse U | Neubauer G | Ramsden N | Rick J | Kuster B | Drewes G
Online reference

Quantitative mass spectrometry in proteomics: a critical review.

Anal. Bioanal. Chem. 2007 Oct; 389(4):1017-31. Epub 2007 Aug 1. DOI: 10.1007/s00216-007-1486-6
Bantscheff M | Schirle M | Sweetman G | Rick J | Kuster B
Online reference

Computational prediction of proteotypic peptides for quantitative proteomics.

Nat Biotechnol. 2007 Jan; 25(1):125-31. Epub 2006 Dec 31. DOI: 10.1038/nbt1275
Mallick P | Schirle M | Chen SS | Flory MR | Lee H | Martin D | Ranish J | Raught B | Schmitt R | Werner T | Kuster B | Aebersold R
Online reference

Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling.

Mol Cell Proteomics. 2006 Dec; 5(12):2211-27. Epub 2006 Sep 6. DOI: 10.1074/mcp.M600147-MCP200
Angrand PO | Segura I | Völkel P | Ghidelli S | Terry R | Brajenovic M | Vintersten K | Klein R | Superti-Furga G | Drewes G | Kuster B | Bouwmeester T | Acker-Palmer A
Online reference

Proteome survey reveals modularity of the yeast cell machinery.

Nature. 2006 Mar 30; 440(7084):631-6. Epub 2006 Jan 22. DOI: 10.1038/nature04532
Gavin AC | Aloy P | Grandi P | Krause R | Boesche M | Marzioch M | Rau C | Jensen LJ | Bastuck S | Dümpelfeld B | Edelmann A | Heurtier MA | Hoffman V | Hoefert C | Klein K | Hudak M | Michon AM | Schelder M | Schirle M | Remor M | Rudi T | Hooper S | Bauer A | Bouwmeester T | Casari G | Drewes G | Neubauer G | Rick JM | Kuster B | Bork P | Russell RB | Superti-Furga G
Online reference

Scoring proteomes with proteotypic peptide probes.

Nat Rev Mol Cell Biol. 2005 Jul; 6(7):577-83. DOI: 10.1038/nrm1683
Kuster B | Schirle M | Mallick P | Aebersold R
Online reference

Covalent cross-links between the gamma subunit (FXYD2) and alpha and beta subunits of Na,K-ATPase: modeling the alpha-gamma interaction.

J Biol Chem. 2005 May 6; 280(18):18291-301. Epub 2005 Mar 2. DOI: 10.1074/jbc.M500080200
Füzesi M | Gottschalk KE | Lindzen M | Shainskaya A | Kuster B | Garty H | Karlish SJ
Online reference

A proteome-wide approach identifies sumoylated substrate proteins in yeast.

J Biol Chem. 2004 Oct 1; 279(40):41346-51. Epub 2004 Jul 30. DOI: 10.1074/jbc.M407950200
Panse VG | Hardeland U | Werner T | Kuster B | Hurt E
Online reference

Phospho.ELM: a database of experimentally verified phosphorylation sites in eukaryotic proteins.

BMC Bioinformatics. 2004 Jun 22; 5:79. DOI: 10.1186/1471-2105-5-79
Diella F | Cameron S | Gemünd C | Linding R | Via A | Kuster B | Sicheritz-Pontén T | Blom N | Gibson TJ
Online reference

Femtomol sensitivity post-digest (18)O labeling for relative quantification of differential protein complex composition.

Rapid Commun Mass Spectrom. 2004; 18(8):869-76. DOI: 10.1002/rcm.1418
Bantscheff M | Dümpelfeld B | Kuster B
Online reference

Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network.

J Biol Chem. 2004 Mar 26; 279(13):12804-11. Epub 2003 Dec 15. DOI: 10.1074/jbc.M312171200
Brajenovic M | Joberty G | Kuster B | Bouwmeester T | Drewes G
Online reference

A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway.

Nat Cell Biol. 2004 Feb; 6(2):97-105. Epub 2004 Jan 25. DOI: 10.1038/ncb1086
Bouwmeester T | Bauch A | Ruffner H | Angrand PO | Bergamini G | Croughton K | Cruciat C | Eberhard D | Gagneur J | Ghidelli S | Hopf C | Huhse B | Mangano R | Michon AM | Schirle M | Schlegl J | Schwab M | Stein MA | Bauer A | Casari G | Drewes G | Gavin AC | Jackson DB | Joberty G | Neubauer G | Rick J | Kuster B | Superti-Furga G
Online reference

ERCC1/XPF removes the 3' overhang from uncapped telomeres and represses formation of telomeric DNA-containing double minute chromosomes.

Mol Cell. 2003 Dec; 12(6):1489-98. DOI: 0.1016/S1097-2765(03)00478-7
Zhu XD | Niedernhofer L | Kuster B | Mann M | Hoeijmakers JH | de Lange T
Online reference

Profiling core proteomes of human cell lines by one-dimensional PAGE and liquid chromatography-tandem mass spectrometry.

Mol Cell Proteomics. 2003 Dec; 2(12):1297-305. Epub 2003 Oct 6. DOI: 10.1074/mcp.M300087-MCP200
Schirle M | Heurtier MA | Kuster B
Online reference

ELM server: A new resource for investigating short functional sites in modular eukaryotic proteins.

Nucleic Acids Res. 2003 Jul 1; 31(13):3625-30. DOI:10.1093/nar/gkg545
Puntervoll P | Linding R | Gemünd C | Chabanis-Davidson S | Mattingsdal M | Cameron S | Martin DM | Ausiello G | Brannetti B | Costantini A | Ferrè F | Maselli V | Via A | Cesareni G | Diella F | Superti-Furga G | Wyrwicz L | Ramu C | McGuigan C | Gudavalli R | Letunic I | Bork P | Rychlewski L | Kuster B | Helmer-Citterich M | Hunter WN | Aasland R | Gibson TJ
Online reference

Affinity purification-mass spectrometry. Powerful tools for the characterization of protein complexes.

Eur J Biochem. 2003 Feb; 270(4):570-8. DOI:10.1046/j.1432-1033.2003.03428.x
Bauer A | Kuster B
Online reference

Unconventional tethering of Ulp1 to the transport channel of the nuclear pore complex by karyopherins.

Nat Cell Biol. 2003 Jan; 5(1):21-7. DOI:10.1038/ncb893
Panse VG | Kuster B | Gerstberger T | Hurt E
Online reference

An improved two-step calibration method for matrix-assisted laser desorption/ionization time-of-flight mass spectra for proteomics.

Rapid Commun Mass Spectrom. 2002; 16(19):1892-5. DOI:10.1002/jms.416
Bantscheff M | Duempelfeld B | Kuster B
Online reference

90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors.

Mol Cell. 2002 Jul; 10(1):105-15. DOI:10.1016/S1097-2765(02)00579-8
Grandi P | Rybin V | Bassler J | Petfalski E | Strauss D | Marzioch M | Schäfer T | Kuster B | Tschochner H | Tollervey D | Gavin AC | Hurt E
Online reference

A transmembrane tight junction protein selectively expressed on endothelial cells and platelets.

J Biol Chem. 2002 May 3; 277(18):16294-303. Epub 2002 Feb 14. DOI:10.1074/jbc.M111999200
Nasdala I | Wolburg-Buchholz K | Wolburg H | Kuhn A | Ebnet K | Brachtendorf G | Samulowitz U | Kuster B | Engelhardt B | Vestweber D | Butz S
Online reference

Tyrosine phosphorylation mapping of the epidermal growth factor receptor signaling pathway.

J Biol Chem. 2002 Jan 11; 277(2):1031-9. Epub 2001 Oct 30. DOI:10.1074/jbc.M109992200
Steen H | Kuster B | Fernandez M | Pandey A | Mann M
Online reference

Functional organization of the yeast proteome by systematic analysis of protein complexes.

Nature. 2002 Jan 10; 415(6868):141-7. DOI:10.1038/415141a
Gavin AC | Bösche M | Krause R | Grandi P | Marzioch M | Bauer A | Schultz J | Rick JM | Michon AM | Cruciat CM | Remor M | Höfert C | Schelder M | Brajenovic M | Ruffner H | Merino A | Klein K | Hudak M | Dickson D | Rudi T | Gnau V | Bauch A | Bastuck S | Huhse B | Leutwein C | Heurtier MA | Copley RR | Edelmann A | Querfurth E | Rybin V | Drewes G | Raida M | Bouwmeester T | Bork P | Seraphin B | Kuster B | Neubauer G | Superti-Furga G
Online reference

Mass spectrometry allows direct identification of proteins in large genomes.

Proteomics. 2001 May; 1(5):641-50.DOI:10.1002/1615-9861(200104)1:5<641::AID-PROT641>3.0.CO;2-R
Kuster B | Mortensen P | Andersen JS | Mann M
Online reference

Glycosylation analysis of gel-separated proteins.

Proteomics. 2001 Feb; 1(2):350-61.DOI:10.1002/1615-9861(200102)1:2<350::AID-PROT350>3.0.CO;2-7
Kuster B | Krogh TN | Mørtz E | Harvey DJ
Online reference

Quadrupole time-of-flight versus triple-quadrupole mass spectrometry for the determination of phosphopeptides by precursor ion scanning.

J Mass Spectrom. 2001 Jul; 36(7):782-90. DOI:10.1002/jms.174
Steen H | Kuster B | Mann M
Online reference

Detection of tyrosine phosphorylated peptides by precursor ion scanning quadrupole TOF mass spectrometry in positive ion mode.

Anal Chem. 2001 Apr 1; 73(7):1440-8.DOI:10.1021/ac001318c
Steen H | Kuster B | Fernandez M | Pandey A | Mann M
Online reference

Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry.

EMBO J. 2000 Dec 1; 19(23):6569-81.DOI:10.1093/emboj/19.23.6569
Ajuh P | Kuster B | Panov K | Zomerdijk JC | Mann M | Lamond AI
Online reference

Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres.

Nat Genet. 2000 Jul; 25(3):347-52.DOI:10.1038/77139
Zhu XD | Kuster B | Mann M | Petrini JH | de Lange T
Online reference

Composition of N-linked carbohydrates from ovalbumin and co-purified glycoproteins.

J Am Soc Mass Spectrom. 2000 Jun; 11(6):564-71. DOI:10.1016/S1044-0305(00)00122-7
Harvey DJ | Wing DR | Kuster B | Wilson IB
Online reference

A new variant of the gamma subunit of renal Na,K-ATPase. Identification by mass spectrometry, antibody binding, and expression in cultured cells.

J Biol Chem. 2000 Jun 16; 275(24):18441-6. DOI:10.1074/jbc.M001411200
Kuster B | Shainskaya A | Pu HX | Goldshleger R | Blostein R | Mann M | Karlish SJ
Online reference

Characterisation of tissue-specific oligosaccharides from rat brain and kidney membrane preparations enriched in Na+,K+-ATPase.

Glycoconj J. 1999 Aug; 16(8):437-56. DOI:10.1023/A:1007078511110
Clark RA | Kuster B | Benallal M | Anner BM | Dwek RA | Harvey DJ | Wing DR
Online reference

Glycosylation of natural human neutrophil gelatinase B and neutrophil gelatinase B-associated lipocalin.

Biochemistry. 1999 Oct 19; 38(42):13937-50. DOI:110.1021/bi991162e
Rudd PM | Mattu TS | Masure S | Bratt T | Van den Steen PE | Wormald MR | Kuster B | Harvey DJ | Borregaard N | Van Damme J | Dwek RA | Opdenakker G
Online reference

18O-labeling of N-glycosylation sites to improve the identification of gel-separated glycoproteins using peptide mass mapping and database searching.

Anal Chem. 1999 Apr 1; 71(7):1431-40. DOI:10.1021/ac981012u
Kuster B | Mann M.
Online reference

Oligosaccharides of recombinant mouse gelatinase B variants.

Biochim Biophys Acta. 1998 Nov 27; 1425(3):587-98. DOI:10.1016/S0304-4165(98)00113-5
Van den Steen P | Rudd PM | Proost P | Martens E | Paemen L | Kuster B | van Damme J | Dwek RA | Opdenakker G
Online reference

Structural determination of N-linked carbohydrates by matrix-assisted laser desorption/ionization-mass spectrometry following enzymatic release within sodium dodecyl sulphate-polyacrylamide electrophoresis gels: application to species-specific glycosylation of alpha1-acid glycoprotein.

Electrophoresis. 1998 Aug; 19(11):1950-9. DOI:-
Kuster B | Hunter AP | Wheeler SF | Dwek RA | Harvey DJ
Online reference

Identifying proteins and post-translational modifications by mass spectrometry.

Curr Opin Struct Biol. 1998 Jun; 8(3):393-400. DOI:10.1016/S0959-440X(98)80075-4
Kuster B | Mann M
Online reference

Partially glucose-capped oligosaccharides are found on the hemoglobins of the deep-sea tube worm Riftia pachyptila.

Glycobiology. 1998 Jul; 8(7):663-73. DOI:-
Zal F | Kuster B | Green BN | Harvey DJ | Lallier FH
Online reference

Perspectives in the glycosciences--matrix-assisted laser desorption/ionization (MALDI) mass spectrometry of carbohydrates.

Glycoconj J. 1998 Apr;15(4):333-8. DOI:10.1023/A:1006913616252
Harvey DJ | Kuster B | Naven TJ
Online reference

Sequencing of N-linked oligosaccharides directly from protein gels: in-gel deglycosylation followed by matrix-assisted laser desorption/ionization mass spectrometry and normal-phase high-performance liquid chromatography.

Anal Biochem. 1997 Jul 15; 250(1):82-101. DOI:10.1006/abio.1997.2199
Kuster B | Wheeler SF | Hunter AP | Dwek RA | Harvey DJ
Online reference

Oligosaccharide sequencing technology.

Nature. 1997 Jul 10; 388(6638):205-7. DOI:10.1038/40677
Rudd PM | Guile GR | Kuster B | Harvey DJ | Opdenakker G | Dwek RA
Online reference

Ammonium containing buffers should be avoided during enzymatic release of glycans from glycoproteins when followed by reducing terminal derivatization.

Glycobiology. 1997 Mar; 7(2):vii-ix.DOI:10.1093/glycob/7.2.161-a
Kuster B | Harvey DJ
Online reference

Rapid approach for sequencing neutral oligosaccharides by exoglycosidase digestion and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

J Mass Spectrom. 1996 Oct; 31(10):1131-40.DOI:10.1002/(SICI)1096-9888(199610)31:10<1131::AID-JMS401>3.0.CO;2-R
Kuster B | Naven TJ | Harvey DJ
Online reference

Identification of oligosaccharides by matrix-assisted laser desorption ionization and electrospray MS.

Biochem Soc Trans. 1996 Aug; 24(3):905-12.DOI:-
Harvey DJ | Naven TJ | Kuster B
Online reference

Effect of the reducing-terminal substituents on the high energy collision-induced dissociation matrix-assisted laser desorption/ionization mass spectra of oligosaccharides.

Rapid Commun Mass Spectrom. 1996; 10(13):1645-51.DOI:10.1002/(SICI)1097-0231(199610)10:13<1645::AID-RCM664>3.0.CO;2-N
Kuster B | Naven TJ | Harvey DJ
Online reference

Comparison of fragmentation modes for the structural determination of complex oligosaccharides ionized by matrix-assisted laser desorption/ionization mass spectrometry.

Rapid Commun Mass Spectrom. 1995;9(15):1556-61.DOI:10.1002/rcm.1290091517
Harvey DJ | Naven TJ | Kuster B | Bateman RH | Green MR | Critchley G
Online reference
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Chair of Proteomics and Bioanalytics

Chair of Proteomics and Bioanalytics

NEWS

3 October 2014

Tracking drug action in living cells by thermal profiling and proteomics

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19 Aug 2014

Open PostDoc position in Bioinformatics or Computational Biology

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13 August 2014

Draft of the human proteome featured in Nature Biotechnology

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12 August 2014

Dominic's HD-DDA paper published in MCP - Congrats!

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12 August 2014

Chen's paper published in BMC Bioinformatics

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12 August 2014

Impressive press coverage of 'human proteome' paper

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29 May 2014

ProteomicsDB team publishes mass spectrometry-based draft of the human proteome in Nature

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10 April 2014

Xin's research article now published in J Proteome Res

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16 March 2010

Wolfgang-Paul-Studienpreis for Hannes Hahne

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27 September 2013

DMSO enhances electrospray response, boosting sensitivity of proteomic experiments

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08 August 2013

New research article in Cell Reports

Typical protein profile of tumor cells decoded

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20 May 2013

New research article in Nature Biotechnology

A large synthetic peptide and phosphopeptide reference library for mass spectrometry-based proteomics

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